
INTRODUCTION
In the last two years Glucosamine as a dietary supplement has become increasingly popular with the public as an effective treatment for many musculoskeletal conditions such as osteoarthritis.
Whilst the public perception of the supplement gains in popularity, the current negative research trend surrounding the drug has led health experts to question its effectiveness in the treatment of the conditions mentioned.
BACKGROUND
Glucosamine is used in the formation of glycosaminoglycans, proteoglycans, and glycolipids. These three substances are vital components of the synovial fluid that lubricates a joint and the cartilage that provides the smooth surface at the ends of the bones that form a joint. In some conditions such as osteoarthritis, the cartilage can become worn and the synovial fluid can change from a relatively thick and viscous fluid to one of a more watery consistency.
These factors lead to the painful rubbing of the bone ends in the joint and induces an inflammatory response. It is thought that taking glucosamine in the form of glucosamine sulphate can increase production of glycosaminoglycans, proteoglycans, and glycolipids and therefore repair some of the damage that occurs in the previously mentioned conditions.
The dosage of glucosamine is vital in providing effectual pain relief therefore it is advisable to consult your doctor or specialist to discuss the best dosage and products available that will benefit you as an individual.
Terry O’Brien
Back Trouble UK.
www.backtrouble.co.uk
REFERENCES
Reginster J. Y., Bruyere O, Fraikin G, Henrotin Y. (2005) Current concepts in the therapeutic management of osteoarthritis with Glucosamine. Bull Hosp Jt Dis. 2005, 63, (1-2), pp. 31-36.
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